October 4, 2011

Neena Philips, PhD

                 

 

Professor, Biological Sciences, School of Natural Sciences, Fairleigh Dickinson University

Associate Professor, Biology, School of Natural Sciences, Fairleigh Dickinson University

Assistant Professor, Biochemistry, Georgian Court University

 

Scientist, Cell Biology Lab, Research and Development, Chanel

Research:

Skin firming activity of rhodiola via induction of elastin.

Post-doctoral training:

Dermatology, New York University Medical Center

Photomedicine, Massachusetts General Hospital, Harvard Medical School

Biochemistry, Boston University School of Medicine

Research:

Regulation of expression of elastin, and fibrillin genes by ultraviolet radiation in keratinocytes or fibroblasts; Regulation of type I collagen promoter activity by methylation

 

PhD:

            Biochemistry and Molecular Biology, Thomas Jefferson University

Thesis: Increased a1 (I) procollagen gene expression in tight skin (TSK) mice myocardial fibroblasts is due to the absence of the strong inhibitory effect of a negative regulatory sequence that interacts with AP-1 transcription factor.

 

Courses Taught:

Fairleigh Dickinson University: 

Techniques: Theories and Applications Lecture and Laboratory; Cell Biology Lecture and Laboratory; Recombinant DNA Technology Lecture; Biotechniques Lecture and Laboratory; Microtoxicity/Biochemistry Lecture; Modern Biology Lecture; General Biology I Lecture; General Biology II Lecture and laboratory

Georgian Court University: 

Advanced Cell Biology Lecture and Laboratory; Tissue Culture Lecture and Laboratory; Biochemistry I/II Lecture and Laboratory; Topics in Biochemistry; Integrated Science I and II Lecture and Laboratory; General Biology I Lecture and laboratory

 

Research:

Regulation of extracellular matrix genes and growth factors by potential anti-aging, anti-carcinogenic, and wound repair agents in normal or cancer cells:

            Publications, Presentations, Proposals, Research Collaborator, Mentor to student research

Research Methodology:

Tissue culture: Normal (fibroblasts, keratinocytes, skin equivalents) or cancer (melanoma, renal, mammary, endometrial) cells.

Cell viability: proliferation, toxicity, membrane damage, and apoptosis.

Recombinant DNA Technology: Polymerase chain reaction (PCR), cloning, site

                        directed mutagenesis, plasmid preparation. 

Transcriptional Regulation: Transient transfection of promoter-reporter

(chloramphenicol acetyl transferase, luciferase, beta-galactosidase) plasmids followed by reporter assays; promoter/protein interactions by gel shift and super shift assays.

               mRNA analysis: RNA isolation, cDNA synthesis, and qPCR, RNA interference,Northern blo, RNase protection
               Protein analysis: ELISA, Western blotting, zymograms, immunoprecipitation

  Direct or cellular oxidative stress: Reactive oxygen species, lipid peroxidation, antioxidant activity, antioxidant enzymes.

                Enzyme inhibition kinetics: Matrix metalloproteinases (MMP) and elastase

               Histology: Paraffin embedding, cryostat, slide preparation, H&E staining, and

            Immunoflurescence

               Data analysis: Microsoft Excel

 

Publications:

Original Research:

1.      Philips N, Hwang H, Chauhan S, Leonardi D, Gonzalez S. (2010) Stimulation of cell proliferation, and expression of matrixmetalloproteinase-1 and interluekin-8 genes in dermal fibroblasts by copper. Connective Tissue Res. 51:224-9.

2.      Philips N, Samuel M, Arena R, Chen Y, Conte J, Natrajan P, Haas G, Gonzalez S. (2010) Direct inhibition of elastase and matrixmetalloproteinases, and stimulation of biosynthesis of fibrillar collagens, elastin and fibrillins by xanthohumol. J. Cosmet. Sci. 61:125-32.

3.      Philips N, Conte J, Chen Y, Natrajan P, Taw M, Keller T, Givant J, Tuason M, Dulaj L, Leonardi D, Gonzalez S (2009) Beneficial regulation of matrixmetalloproteinases and its inhibitors, fibrillar collagens and transforming growth factor-b by P. leucotomos, directly or in dermal fibroblasts, ultraviolet radiated fibroblasts, and melanoma cells. Arch. Derm. Res. 301:487-495. 

4.      Philips N, Tuason M, Chang T, Lin Y, Tahir M, Rodriguez SG (2009) Differential effects of ceramide on cell viability and extracellular matrix remodeling in keratinocytes and fibroblasts. Skin Pharmacol. Physiol. 22:151-157.

5.      Philips N, Dulaj L, Upadhya T. (2009) Growth inhibitory mechanism of ascorbate and counteraction of its matrix metalloproteinases-1 and transforming growth factor-beta stimulation by gene silencing or P. leucotomos. AntiCancer Res. 29:3233-8.

6.      Philips N, Tahir M, Stellatella J, Stephan K, Givant J, Zhou L, Costa A, Taw M (2009) Differential regulation of growth factors and matrix metalloproteinase-1 by estrogen, progesterone, and tamoxifen in normal and cancerous endometrial cells. J. Cancer Mol. 4: 169-173.

7.      Philips N, Arena R, Yarlagadda S. (2009) Inhibition of ultraviolet radiation mediated extracellular matrix remodeling in fibroblasts by transforming growth factor-b. BIOS 80: 1-5.

8.      Brieva A, Philips N, Tejedor R, Guerrero A, Pivel JP, Alonso-Lebrero JL, Gonzalez S. (2008) molecular basis for the regenertive properties of the mollusk criptomphalus aspersa. Skin Pharmacol. and Physiol. 21:15-22.

9.      Astner S, Wu A, Chen J, Philips N, Rius-Diaz F, Parrado C, Mihm MC, Goukassian DA, Pathak MA, González, S. (2007) Dietary lutein/zeaxanthin reduces photoaging and photocarcinogenesis in chronically UVB irradiated SKH -1 hairless mice. Skin Pharmacol. and Physiol. 20:283-281.

10.  Philips N, Keller T, Hendrix C, Hamilton S, Arena R, Tuason M, Gonzalez S. (2007) Regulation of the extracellular matrix remodeling by lutein in dermal fibroblasts, melanoma cells, and ultraviolet radiation exposed fibroblasts. Arch. Dermatol. Res. 299: 373-379.

11.  Philips N, Keller T, Holmes C. (2007) Reciprocal effects of ascorbate on cancer cell growth and the expression of matrix metalloproteinases and transforming growth factor-beta. Cancer Letters 256:49-55.

12.  Philips N, Burchill D, O’Donoghue D, Keller T, and Gonzalez S. (2004) Identification of benzene metabolites in dermal fibroblasts: Regulation of cell viability, apoptosis, lipid peroxidation, and expression of MMP-1 and elastin by benzene metabolites. Skin Pharmacol. and Physiol. 17:147-152.

13.  Philips N, Keller T, and Gonzalez S. (2004) TGF b like regulation of matrix metalloproteinases by anti transforming growth factor-b and anti transforming growth factor-b1 antibodies in dermal fibroblasts: implications to wound healing. Wound Repair Regeneration 12:53-59.

14.  Philips N, and McFadden K. (2004) Inhibition of transforming growth factor-beta and matrix metalloproteinases by estrogen and prolactin in breast cancer cells. Cancer Letters 206: 63-68.

15.  Philips N. (2003) An anti TGF-b increased the expression of transforming growth factor-b, matrix metallproteinase-1, and elastin, and its effects were antagonized by ultraviolet radiation in epidermal keratinocytes. J. Dermatol. Sci. 33:177-179.

16.  Philips N, Smith J, Keller T, and Gonzalez S. (2003) Predominant effects of Polypodium leucotomos on membrane integrity, lipid peroxidation, and expression of elastin and matrixmetalloproteinase-1 in ultraviolet radiation exposed fibroblasts, and keratinocytes. J. Dermatol. Sci. 32:1-9.

17.  Philips N. and Devaney J. (2003) Beneficial regulation of type I collagen and matrixmetalloproteinase –1 expression by estrogen, progesterone, and its combination in skin fibroblasts. J. American Aging Association 26:59-62.

18.  Philips N and Onwubalili N. (2002) Anti transforming growth factor-beta (TGF-b) increases the expressions of matrix metalloproteinase-1 (MMP-1) and growth factors in a renal adenocarcinoma cell line. BIOS 73: 86-90.

Review Articles:

  1. Gonzalez S, Gilaberte Y, Philips N, Juarranz A. (2011) Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers. Advances in Nutriceutical Res.

20.  Philips N, Auler S, Hugo R, Gonzalez S. (2011) Beneficial regulation of matrixmetalloproteinases for skin health. Enzyme Res. 2011 (427285): 1-5

21.   Gonzalez S, Gilaberte Y, Philips N, Juarranz A. (2010) Current trends in photoprotection – a new generation of photoprotectors. The Open Derm. Journal. 5: 1-9.

22.  Gonzalez S, Gilaberte Y, and Philips N. (2010) Mechanistic insights in the use of a Polypodium leucotomos extract as an oral and topical photoprotective agent. Photochem. Photobiol. Sci. 9:559-563.

23.  Philips N. (2010) Counteraction of skin inflammation and aging or cancer by polyphenols. Anti-inflammatory and Anti-allergy Agents in Medicinal Chemistry. Editor: Francesco Epifano. Bentham Science Publishers Ltd.

24.  Gonzalez S, Philips N, and Gilaberte Y. (2010) Photoprotection: Update in UV filter  molecules, the “new wave” of sunscreens. Dermatol. Venereol. 145:515-23

25.  Philips N. (2009) Biochemistry Go-tutorials: Making solutions – concepts and problems. WileyPLUS

26.  Philips N. (2009) Reciprocal effects of ascorbate on cancer cell growth and the expression of matrix metalloproteinases and transforming growth factor-beta: Modulation by gene silencing or P. leucotomos. Hanbook of Vitamin C Research: Daily Requirements, Dietary Sources, and Adverse Effects. Editors: Hubert Kucharski and Julek. Nova Science Publishers Inc.

27.  Philips N. (2009) Experimental physiology in anti-skin aging. Skin Anatomy and Physiology Research Development. Editor: Frank Columbus. Nova Science Publishers Inc.

28.  Goodner J, Patil U, Lim Y, Yarlagadda S, Castro A, Gonzales S, and Philips N. (2008) Coating on micronized titanium dioxide increases safety and maintains efficacy as sunscreen filter. J. Plastic Dermatol. 4:21-22.

29.  Bautista M, Lockett F, Mecca J, Sawatdeekhachornphat W, Castro A, Yarlagadda S, Gonzales S, and Philips N. (2008) The use of antisense oligonucleotides in skin lightening products. J. Plastic Dermatol.  4:17-19.

 

Presentations:

  1. Philips N. (2011) Direct and Cellular Protection of Extracellular Matrix Proteins by Nicotinamide, and its Derivatives.

Oral: Target Meeting (Molecular targets and mechanism of aging), WebConference

2.      Philips N. (2011) Student learning outcome assessment.

Oral: University College Faculty meeting, FDU, Teaneck, NJ.

3.      Philips N. (2010) Photoprotective mechanism of niacinamide via the beneficial regulation of extracellular matrix and heat shock proteins.

Poster: American Society of Cell Biology annual meeting, PA.

4.      Philips N and Gonzalez S. (2010) Beneficial regulation of expression of extracellular matrix proteins and transforming growth factor-b in dermal fibroblasts, and epidermal keratinocytes by Polypodium leucotomos.

            Oral: Annual Scientific Seminar of Society of Cosmetic Chemists, NY.

5.      Philips N. (2010) Anti skin aging, anti-cancer and wound healing target genes and therapeutics via circle of academia-industry-professional organizations.

            Oral: Science Technology Engineering and Mathematics Event, NJ.

6.      Philips N. (2010) Reciprocal relationship between cell death versus heat shock proteins and matrixmetalloproteinases in normal and cancer cells.

Poster: American Society of Biochemistry and Molecular Biology annual meeting, CA.

7.      Philips N. (2009) Inhibition of cancer cell growth and extracellular matrix remodeling by P. leucotomos and ascorbate.

            Oral: Bioconference Live, NJ.

  1. Philips N. (2009) Aging, wound healing and cancer.

            Oral: FDU Biology Seminar, NJ

9.       Philips N. (2009) Inflammation; Immunity: Antibodies; signaling pathways that control gene activity.

            Oral: Presperse Inc. Education Session, NJ.

  1. Philips N. (2008) Photoaging, and cancer treatment by gene silencing or micronutrients.

            Poster: Drug Discovery and Development of Innovative Therapeutics annual

            meeting, MA.      

  1. Philips N. (2008) Anti-skin aging and cancer.

            Oral: FDU Biology Seminar, NJ.

  1. Philips N. (2008). Experimental biochemistry in anti-skin aging. Cosmetiscope 14:4.

            Oral: Society of Cosmetic Chemists monthly meeting, NJ.

  1. Philips N. (2007) Semester-long application-based investigative project, in modern cell biology, for broader learning outcomes session (Science Education).

            Poster: American Society of Cell Biology annual meeting, Washington DC.

  1. Philips N. (2007) Regulation of the extracellular matrix remodeling by lutein in dermal fibroblasts, melanoma cells, and ultraviolet radiation exposed fibroblasts. (Cancer drug discovery and development session).

            Poster: Drug Discovery and Development of Innovative Therapeutics annual

            meeting, MA.

  1. Philips N. (2007) Differential dose dependent effects of ascorbate on cancer cell toxicity or proliferation by ascorbate; Regulation of matrix metalloproteinases and transforming growth factor-beta. Expt. Biol. LB98.

            Poster:  American Society of Biochemistry and Molecular Biology annual meeting, Washington DC.

  1. Philips N. (2006) The cellular and molecular biology of aging and cancer.

            Oral: FDU Biology Seminar, NJ.

  1. Philips N, Keller T, Smith J, Gonzalez S. (2003) Regulation of matrix metalloproteinases (MMPs), and tissue inhibitors of matrix metalloproteinases (TIMPs) by anti transforming growth factor-b antibodies, lutein and Polypodium leucotomos.  Mol. Cell. Proteonomics: 2: 923.

Oral: International Union of Biochemistry and Molecular Biology world congress, Canada.

  1. Philips N. (2003) Skin anti-aging and anti-carcinogenic effects of lutein, and Polypodium leucotomos. J. American Aging.

            Oral: American Aging Association annual meeting, MD.

  1. Philips N, Devaney J, Smith J, Hamilton S, Gonzalez S. (2002) Hormones, Polypodium leucotomos, and lutein, respectively, regulate expression of extracellular matrix proteins in skin fibroblasts. Biogerontology 3:93.

            Oral: European Congress of Biogererontology annual meeting, Italy.

20.  Philips N and Devaney J. (2001) Hormone replacement therapy increases type I collagen in dermal fibroblasts by stimulating transforming growth factor-beta. J. American Aging 24:129.

            Poster: American Aging Association/American College of clinical gerontology/American                   Federation of Aging Research annual meeting, WI.

21.  Philips N, Burchill D, O’Donoghue D, Gonzalez S. (2001) Dermal fibroblasts convert benzene to non-phenolic compounds that are less toxic than the phenolic metabolites of benzene. J. Invest. Dermatol. 117: 481.

            Poster: Society of Investigative Dermatology annual meeting, Washington DC.

 

Research Funding:

  1. Philips N. (2010) Regulation of chemical, cellular, and gene targets by actives for skin health, anti-skin aging and improved wound healing. Presperse LLC, Inc. ($10,000).
  2. Philips N. (2010) Regulation of expression of collagen and elastin genes by copper. Cupron Medical Inc and Cupron Scientific. ($5000).
  3. Philips N. (2010) Skin photoprotection, anti-aging, and anti-cancer mechanism of Hop extract. Hopsteiner, SS Steiner, Inc. ($7500)
  4. Philips N. (2009) Inhibition of angiogenesis and immune cell preservation in cancer management by ascorbate and P. leucotomos. Grant-in-Aid program, Fairleigh Dickinson University. ($2,969).
  5. Philips N. (2008) Investigation and management of ascorbate effects in cancer treatment. Grant-in-Aid program, Fairleigh Dickinson University. ($2,990)
  6. Philips N. (2008) Improvement of epidermal barrier function and prevention of tumorigenesis by Polypodium leucotomos, via anti-inflammatory and anti-angiogenic mechanisms. Research Release time, Fairleigh Dickinson University. (three credits).
  1.  Philips N. (2008) Molecule 168 and derivatives (Niacin derivatives): Regulation of extracellular matrix and heat shock proteins. Industrial Farmaceutica Cantabria (IFC). ($10,000).

8.      Philips N. (2008) Anti-inflammatory and antiangiogenic mechanism of Polypodium leucotomos. Industrial Farmaceutica Cantabria (IFC). ($6,500).

9.      Philips N. (2008) Improvement of epidermal barrier function by Polypodium leucotomos in preventing skin photo-aging. Industrial Farmaceutica Cantabria (IFC). ($6,500).

10.  Philips N. (2007) Regulation of extracellular matrix, heat shock proteins, and transforming growth factor-b (TGF-b) by Polypodium leucotomos (PL) in preventing skin aging. Industrial Farmaceutica Cantabria (IFC). ($30,000).

  1. Philips N. (2007) Regulation of extracellular matrix, heat shock proteins, and transforming growth factor-b (TGF-b) by Polypodium leucotomos (PL) in preventing skin aging. Research Release time, Fairleigh Dickinson University. (six credits).
  2. Philips N. (2007) Investigation of cancer mechanisms in an ascorbate model: Regulation by lutein and specific gene silencing. Grant-in-Aid program, Fairleigh Dickinson University. ($2,500)  
  3. Philips N. (2007) Elastin gene silencing in keratinocytes for the management of solar skin aging. SEED grant, Fairleigh Dickinson University. ($3,900)

 

 

FDU-Spotlight Faculty Metro, 2006:

“Name: Neena Philips, PhD
Title: Associate Professor of Biological Sciences-University College
Campus: Metropolitan
How long have you been at FDU?

Since the start of Fall 2006
If you could meet anyone in the world, whom would you pick? Why?

My Dad who has passed on: he is the basis to everything I was, am, and will be.
One of the things I have in my refrigerator all the time is ...

Coffee grind
What book or film did you recently enjoy? Why would you recommend it?

Letters for Emily by Camron Wright: for its life-lessons and reminder of my Dad’s wisdom to me. Also, Death and Dying by Elizabeth Kubler-Ross: for its insight into the detachment of a dying person from his/her environment.
Something I’ve always wanted to learn is ...

Technological advances in my field, Biochemistry/Cellular/Molecular Biology
I collect ...

Insights, poems, wisdom, thoughts
Things that brighten my day are ...

Harmony between people.
Complete the phrase: People would be surprised to know that I ...

Was a Principal Scientist at Chanel, chose to remain in teaching, and miss Chanel sometimes. Also, people would be surprised to know that I value my Mom’s strength and advice.
What profession other than your own would you most like to attempt, and what profession would you want nothing to do with?

I would attempt writing of non-fiction/non science, based on my life experience. I would not want to be in professions that need physical strength/labor for I prefer reading/writing/teaching.”

 

 

Service:

 University programs or courses, STEM community event, University or college committees, Learning outcomes assessment, Personnel review, Open house or major related activity, Professional society membership, Student (internal and external) mentor, Academic programs reviewer, Scholarly work reviewer (manuscripts, textbooks, research proposals)

  1. STEM community event organizer: integration of higher education, high school, industry and professional organizations
  2. Hand Book Committee member
  3. Library Committee member
  4. Research Release Time Committee
  5. Student Success Team member
  6. Campus Standard Committee
  7. Wellness Committee
  8. Mental Health Committee
  9. University College research program
  10. University President’s lunch forums; University: Convocation and commencement;

Campus Provost’s meetings, University College and Department meetings

  1. Learning outcomes assessment of courses, New course development, Open house or major-related
  2. Personnel review
  3. Reviewer of manuscripts, textbooks, research proposals:

Academic Press/Elsevier

BioFactors

British Journal of Cancer (Blackwell Publishing)

BBA-Molecular Cell Research (Elsevier)

Cancer Informatics (Libertas Academica)

Cell Biochemistry and Function (Wiley Interscience)

Current Cancer Drug Targets (Bentham Science Publishers)

Clinical Cosmetic and Investigational Dermatology (Dove Medical Press)

Clinical Interventions in Aging (Dove medical Press)

Dermatology Research and Practice (Hindawi Publishers)

Ecotoxicology and Environmental Safety (Elsevier)

Experimental Dermatology (Wiley Blackwell)

Food and Chemical Toxicology

Integrative Cancer Therapies (Sage Journal)

Innovational Research Incentive Scheme (Netherland

      Organization for Scientific Research)

      International Journal of General Medicine (Dove Medical Press)

Journal Amino Acids

Journal of Cosmetic Science (Society of Cosmetic Chemists)

Journal of Dermatological Science (Elsevier)

Journal of Medicinal Foods

O’Donnell and Associates for Academic Press

      The Open Biotechnology Journal (Bentham Science Publishers)

Patient Preference and Adherence (Dove Medical Press)

Research and Research in Tropical Medicine (Dove Medical Press)

Special issue of Current Drug Targets (Bentham Science Publishers)

Skin Pharmacology and Physiology (Karger)

 

Mentor, Students Research and Presentations:

Meetings:        Hudson Bergen American Chemical Society

School of Natural Sciences Seminar

American Women in Science

Honors Research day

New Jersey Academy of Sciences

Sigma Xi Research Symposium

1.      Kogan A and Philips N.  (2011) Direct and cellular protection of extracellular matrix proteins by nicotinamide, and its derivatives. (Honors Research Seminar, FDU Biology Seminar, Hudson-Bergen American Chemical Society).

2.      Famulare C and Philips N.  (2011) Anti-inflammatory effect of niacinamide for skin health (Hudson-Bergen American Chemical Society).

3.      Parakandi H and Philips N.  (2011) Optimization of types I, III and V collagen mRNA detection by quantitative polymerase chain reaction. (FDU Biology Seminar, Hudson-Bergen American Chemical Society, Society of Cosmetic Chemistry Seminar).

4.      Han J, Han S, Ferrer R and Philips N.  (2011) Copper stimulates cell proliferation by stimulating nuclear factor kB and vascular endothelial growth factor and inhibiting apoptosis. (Hudson-Bergen American Chemical Society).

5.      Ministro A., Morrison K., Nieves Z., Kogan A., Borkow G. and Philips N. (2011) Copper oxide particle size in the regulation of expression of extracellular matrix proteins in dermal fibroblasts. (FDU Biology Seminar, Hudson-Bergen American Chemical Society, Society of Cosmetic Chemistry Seminar).

6.      Siomyk H, Musbah M, Williams K and Philips N. (2011) Niacinamide promotes wound healing via inhibition of apoptosis and NF-KB promoter in dermal fibroblast cells. (Hudson-Bergen American Chemical Society).

7.      Patel S and Philips N. (2011) Determination of direct antioxidant activity of plant extracts. (FDU Biology Seminar, Hudson-Bergen American Chemical Society, Society of Cosmetic Chemistry Seminar).

8.      Auler S. and Philips N.  (2011) Beneficial regulation of extracellular matrix by p. leucotomos in epidermal keratinocytes. (Hudson-Bergen American Chemical Society).

9.      Nieves Z and Philips N.  (2011) Ascorbate and P. leucotomos inhibit angiogenesis and oxidative stress in melanoma cells. (FDU Biology Seminar, Hudson-Bergen American Chemical Society).

  1. Leonida MD, Haas GJ and Philips N. (2010) Composite materials with antimicrobial activity based on biopolymers (Biommedd-International conference on biomaterials, Sept 2010)
  2. Hwang H, Bynum D and Philips N. (2010) Photoprotective effects of P. leucotomos via epidermal keratinocytes (National Council for Undergraduate Research).

12.  Shah D, Auler S and Philips N. (2010) Direct antioxidant effect of plant or algal extracts (STEM Community Event, FDU Biology Seminar, Hudson-Bergen American Chemical Society).

13.  Mainiero J, Biagini S and Philips N. (2010) Strengthing of extracellular matrix by algal or plant extract (STEM Community Event, FDU Biology Seminar, Hudson-Bergen American Chemical Society).

14.  Hawkins U and Philips N. (2010) Inhibition of elastase activity by algal extract (STEM Community Event, Hudson-Bergen American Chemical Society).

15.   Hwang H, Bynum D, Ekhelar A and Philips N. (2010) Direct elastase inhibition and stimulation of fibrillins, tissue inhibitors of matrixmetalloproteinases, and transforming growth factor-b by P. leucotomos extract in epidermal keratinocytes (STEM Community Event, Hudson-Bergen American Chemical Society).

16.  Gopinathan S,  Syeda S, Perez E and Philips N. (2010) Photoprotective mechanism of P. leucotomos via improved skin barrier function (STEM Community Event, Hudson-Bergen American Chemical Society).

17.   Buturla A, Philips N. (2010) Inhibitory effect of P. leucotomos on vascular endothelial growth factor expresison in keratinocytes (STEM Community Event, Hudson-Bergen American Chemical Society).

18.   Pininti S and Philips N. (2010) Regulation of vascular endothelial growth factor expression by ascorbic acid and Polypodium leucotomus extract in melanoma (STEM Community Event, Hudson-Bergen Chemical Society).

19.  Tatapudi S, Riccardello K, Philips N. (2010) Regulation of cancer cell oxidative stress by ascorbic acid and P. leucotomous in melanoma cells (STEM Community Event, Hudson-Bergen Chemical Society).

20.   Gopinathan S, Syeda M,  Buturla A, Perez E and  Philips N. (2010) Photoprotective mechanism of P. leucotomos via regulation of heat shock proteins and vascular endothelial growth factor in epidermal cells (FDU Biology Seminar).

  1. Tatapudi S, Srikanth P,  Riccardello K, Philips N. (2010) Regulation of oxidative stress, vascular endothelial growth factor, and intercellular adhesion molecule-1 by ascorbic acid and P. leucotomous in melanoma cells (FDU Biology Seminar).

22.  Chauhan S and Philips N. (2010) Stimulation of cell proliferation and expression of matrixmetalloproteinase-1 and interluekin-8 genes in dermal fibroblasts by copper (STEM Community Event, FDU Biology Seminar). 

23.   Sievers D, Gang V, Nieves Z and Philips N. (2010) Oligo HA stimulates collagen and fibroblasts proliferation for enhanced ECM integrity (STEM Community Event).

24.   Zhou X, Kolatlu S, K Navubothu, Prodduturi A and Philips N. (2010) Kalparine in wound healing (STEM Community Event).

25.   Nguyen N, Le M, Spriggs H, Arteta D and  Philips N. (2010) MJB inhibits cell viability and MMP expression by stimulating oxidative stress in melanoma cells (STEM Community Event).

26.   Parakandi H, Patel S, Joshi L, Sapana P, Philips N. (2010) Analyzing anti-aging activity of Ziyuglucoside I by investigating its effect on cell viability, and  memberane damage and MMP expression in fibroblast cells (STEM Community Event).

27.  Cohen L, Solano O, Torbus A, Washington S and Philips N. (2010) The cancer –proliferative effect of antiluekin-6 via its antioxidant properties (STEM Community Event).

  1. Plaskon P, Pedrick M, Fields T and Philips N. (2009) Epidermal protective effects of vitamin D (Hudson-Bergen Chemical Society).
  2. Baswan, S and Philips N. (2009) Anti-skin aging potential of xanthohumol by

stimulation of fibrillin expression (Hudson-Bergen Chemical Society).

  1. Chauhan, S and Philips N. (2009) Regulation of heat shock proteins by P. leucotomos and its components in skin cells (Hudson-Bergen American Chemical Society).
  2. Dodiya, R and Philips N. (2009) Polyphenols stimulate structural collagens (Hudson-Bergen Chemical Society, FDU Biology Seminar).
  3. Jain, D and Philips N. (2009) Dual protective effects of P. leucotomos and its components on elastin fibers (FDU Biology Seminar, Hudson-Bergen Chemical Society).
  4. Perez E, Kogan A, Yamada E and Philips N. (2009) Regulation of apoptosis for   cell survival by P. leucotomos in ultraviolet radiation exposed keratinocytes (Hudson-Bergen Chemical Society).
  5. Sharma K, Nicolas C, Baswan S and Philips N. (2009) Regulation of collagen,  

elastin and heat shock proteins by caffeic acid (Hudson-Bergen Chemical Society, Society of Cosmetic Chemists Annual Meeting).

  1. Tuason M and Philips N. (2009) Beneficial remodeling of the extracellular matrix by P. leucotomos and its components (Hudson-Bergen American Chemical Society).
  2. Dulaj L and Philips N. (2009) Combination of vitamin C and P. leucotomos is beneficial to cancer therapy (FDU Biology Seminar, Hudson-Bergen Chemical Society).
  3. Hwang H and Philips N. (2009) Copper as environmental pollutant (Bergen County Academy Senior Experience).
  4. Leonida MD, Chauhan S, Philips N. (2009) Potent dual action composites (American chemical society national meeting and exposition)
  5. Natarajan P and Philips N. (2008) Mechanisms of skin regeneration by a mollusk secretion (FDU Biology Seminar, Hudson-Bergen Chemical Society).
  6. Thota S, Yarlagadda S and Philips N. (2008) Large scale plasmid preparation and promoter activity testing (Hudson-Bergen Chemical Society).
  7. Yarlagadda S and Philips N. (2008) Anti skin aging effect of luteolin (Hudson-Bergen Chemical Society).
  8. Conte J, Scorfield J and Philips N. (2008) Screening actives for elastase enzyme inhibition (Hudson-Bergen Chemical Society).
  9. Kogan A and Padilla S and Philips N. (2008) Molecular mechanisms of luteolin’s anticarcinogenic effect (FDU Biology Seminar, Hudson-Bergen Chemical Society).
  10. Semilla A and Philips N. (2008) Gene silencing for photoaging and cancer therapy (FDU Biology Seminar, Hudson-Bergen Chemical Society).
  11. Givant J and Philips N. (2008) Mechanisms regulating differential regulation of MMP-1 by ascorbate (Hudson-Bergen Chemical Society, Bull NJ Acad. Sci 53).
  12. Lin Y, Plaskon P, Chang T and Philips N. (2008) Epidermal differentiation mechanism of ceramide (FDU Biology Seminar, Hudson-Bergen American Chemical Society).
  13. Lee S and Philips N. (2008) Tamoxifen’s effectiveness in endometrial cells (Hudson-Bergen Chemical Society).
  14. Kahodariya J, Mehta N and Philips N. (2008) Role of copper in wound healing (FDU Biology Seminar, Hudson-Bergen Chemical Society).
  15. Chang T and Philips N (2008) Gene regulation by ceramide (Bergen County Academy Senior Experience).
  16. Woo J and Philips N. (2007) Increased expression of elastin in ultraviolet radiation exposed keratinocytes (Hudson-Bergen Chemical Society, SJU Sigma Xi Research Symposium).
  17. Prashanthi N and Philips N. (2007) Regulation of cell viability and matrixmetalloproteinases in lung fibroblasts by xanthohumol (FDU Biology Seminar, Hudson-Bergen Chemical Society, National Collegiate Honors Conference).
  18. Schmidt E, Lescisko A and Philips N. (2007) Oxidative effects of hydrogen peroxide in lung (MRC5) fibroblasts (Hudson-Bergen Chemical Society, SJU Sigma Xi Research Symposium).
  19. Arena R and Philips N. (2007) Identification of anti-carcinogenic agents in the treatment of melanoma (FDU Biology Seminar, Hudson-Bergen Chemical Society, SJU Sigma Xi Research Symposium).
  20. Goldschein E and Philips N. (2007) Regulation of tissue inhibitor of matrixmetalloproteinases by transforming growth factor- beta: Modulation by ultraviolet radiation (Hudson-Bergen American Chemical Society, SJU Sigma Xi Research Symposium, FDU Biology Seminar).
  21. Pitropaki A, Aviles D and Philips N. (2007) Selective inhibition of melanoma cell viability by Polypodium leucotomos (SJU Sigma Xi Research Symposium).
  22. Hourmouzis P, Plaskon P, McKelvey K, Avendano A and Philips N. (2007) Ascorbate in combination with vitamin E in cancer treatment (Hudson-Bergen Chemical Society, SJU Sigma Xi Research Symposium).
  23. Chahine G, Morris M, Shishkova E, Ijbara M and Philips N. (2007) Ascorbic acid inhibits MMP1 expression and reduces cellular viability in vero cells (Hudson-Bergen Chemical Society, SJU Sigma Xi Research Symposium).